Niacinamide

Niacinamide is an active form of vitamin B3 (niacin), and a versatile skincare ingredient praised for its anti-inflammatory, anti-acne, anti-ageing properties. (1)

    • Topical face serums

    • Sprays

    • Oral tablets

  • Short-term side effects can take place with overuse or application of high concentrations, particularly in people with sensitive skin or prone to allergic reactions.

    Symptoms can include redness, itching or burning. If you feel this may apply to you, please consult a dermatologist. (4)

    Oral supplements may be preferable for people with a history of skin allergies.

    Niacinamide serums can also be diluted with other products, such as moisturiser, to avoid applying high concentrations directly to the skin, though most formulations will be fairly dilute already.

What is it used for?

Niacinamide can be used daily as part of your skincare routine. It supports new collagen synthesis and maintenance of important skin factors that naturally deplete with age(2).

Additionally, studies have shown that it can prevent UV damage and hyperpigmentation, as well as regulate oil levels and reduce acne. (3)

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Alice’s Take

“Niacinamide is central to my personal skin routine - I mix it a drop of serum in with my moisturiser and use after cleansing my skin. I find it makes my skin appear smoother and brighter, and reduces spots.”


References:

(1) Cleveland Clinic (2022). Top 6 Benefits of Niacinamide. [online] Cleveland Clinic. Available at: https://health.clevelandclinic.org/niacinamide.

(2) Marques, C., Hadjab, F., Porcello, A., Lourenço, K., Scaletta, C., Abdel-Sayed, P., Hirt-Burri, N., Applegate, L.A. and Laurent, A. (2024). Mechanistic Insights into the Multiple Functions of Niacinamide: Therapeutic Implications and Cosmeceutical Applications in Functional Skincare Products. Antioxidants, [online] 13(4), p.425. doi:https://doi.org/10.3390/antiox13040425.

(3) Matts, P.J., Oblong, J.E. & Bissett, D.L. (2002). A Review of the Range of Effects of Niacinamide in Human Skin. IFSCC 5. Available at: https://www.researchgate.net/profile/Paul-Matts/publication/286270242_A_Review_of_the_range_of_effects_of_niacinamide_in_human_skin/

(4) Vinmec International Hospital. (2024). What are the side effects of niacinamide? [online] Available at: https://www.vinmec.com/eng/blog/what-are-the-side-effects-of-niacinamide-en.

Alice Mckenzie

Medical Student & Contributing Writer

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